I take 100mg/kg of aspirin, NOT salicylic acid, a day to treat idiopathic arthritis. For various reasons I am unable to take other pain relievers to relieve my joint inflammation. Please don't recommend another drug because that's not the question I am asking.
Anyway, my doctor came up with a few recommendations, some of which I follow and others that I don't.
Here they are:
* He told me I could dissolve the tablets in water and that this should help decrease GI irritation and bleeding. I looked it up and studies have shown this to be true. I do NOT follow this because the water then takes like vinegar and is too difficult to down.
* He told me I could take Proton Pump Inhibitors, but I do NOT take these because they are associated with increased risks of developing osteoporosis and other bone problems.
*He told me I could take large doses of Vitamin K2, 10mg a day (MG not MCG) and that this would help with the bleeding cause at such large doses aspirin interferes with Vitamin K dependent clotting factors. I do this and it has helped.
*He told me I could take a dose of Vitamin C that was equivalent to the dose of aspirin I am taking. I do this as well, BUT Vitamin C increases the absorption of Iron and mine is on the high side now.
I don't take the coated tablets because they take longer to absorb and their AUC is reduced.
To be honest, I don't really have much int he way of irritation from the drug; I just get a little bit of nausea every once in a while and occult stool tests have shown only trace amounts of blood in the stool which I am told is not abnormal.
I have ben taking this stuff for so long and I don't wish to switch to anything else. The side effects are minimal, it's cheap, I don't need an official prescription so I don't have to worry about the pharmacy ordering the drug, it works for me.
Anyway, my doctor came up with a few recommendations, some of which I follow and others that I don't.
Here they are:
* He told me I could dissolve the tablets in water and that this should help decrease GI irritation and bleeding. I looked it up and studies have shown this to be true. I do NOT follow this because the water then takes like vinegar and is too difficult to down.
* He told me I could take Proton Pump Inhibitors, but I do NOT take these because they are associated with increased risks of developing osteoporosis and other bone problems.
*He told me I could take large doses of Vitamin K2, 10mg a day (MG not MCG) and that this would help with the bleeding cause at such large doses aspirin interferes with Vitamin K dependent clotting factors. I do this and it has helped.
*He told me I could take a dose of Vitamin C that was equivalent to the dose of aspirin I am taking. I do this as well, BUT Vitamin C increases the absorption of Iron and mine is on the high side now.
I don't take the coated tablets because they take longer to absorb and their AUC is reduced.
To be honest, I don't really have much int he way of irritation from the drug; I just get a little bit of nausea every once in a while and occult stool tests have shown only trace amounts of blood in the stool which I am told is not abnormal.
I have ben taking this stuff for so long and I don't wish to switch to anything else. The side effects are minimal, it's cheap, I don't need an official prescription so I don't have to worry about the pharmacy ordering the drug, it works for me.
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Always, ALWAYS take with food.