What is the greatest thing in this universe/?

Or megatron depending on how you look at it
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The Flying Spaghetti Monster. All hail his noodliness.

Oh, and 42.
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An MLT... mutton, lettuce and tomato - when the lettuce is crisp and the roll is freshly baked.... Oh yeah.
(Billy Crystal, Princess Bride)
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That's rather difficult to say, since we are acquainted with only a vanishingly small corner of the entire universe. My vote would go to idiocy. It permeates everything, it is probably eternal and unconquerable.
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Strawberry milkshakes.
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The atom
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Zombie space ninja pirates. Careful they are both sneaky and dangerous.
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Polar bears, please throw your trash in the recycle trash, because some of us really enjoy looking at polar bears, they are the greatest thing in this universe.
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- Love. Because it makes EACH of Our little "Worlds"- go 'round. :)

Just Me;
-a passing Asteroid.
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sun