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This question relates to the image above.
In contrast to the leading strand, the lagging strand is synthesized as a series of segments called Okazaki fragments. The diagram below illustrates a lagging strand with the replication fork off-screen to the right. Fragment A is the most recently synthesized Okazaki fragment. Fragment B will be synthesized next in the space between primers A and B.
1 - pol III binds to 3' end of primer B
1 -> 2 -> 3 -> 4 -> 5
The Options for 2, 3, 4 and 5 as a flowchart are below, and I have put them in the order that I believe they are correct, but would appreciate review to see if this is correct.
2. pol III moves 5' to 3' adding DNA nucleotides to primer B
3. pol I binds to 5' end of primer A
4. pol I replaces primer A with DNA
5. DNA ligase links fragments A & B
This question relates to the image above.
In contrast to the leading strand, the lagging strand is synthesized as a series of segments called Okazaki fragments. The diagram below illustrates a lagging strand with the replication fork off-screen to the right. Fragment A is the most recently synthesized Okazaki fragment. Fragment B will be synthesized next in the space between primers A and B.
1 - pol III binds to 3' end of primer B
1 -> 2 -> 3 -> 4 -> 5
The Options for 2, 3, 4 and 5 as a flowchart are below, and I have put them in the order that I believe they are correct, but would appreciate review to see if this is correct.
2. pol III moves 5' to 3' adding DNA nucleotides to primer B
3. pol I binds to 5' end of primer A
4. pol I replaces primer A with DNA
5. DNA ligase links fragments A & B
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Yep, you got it.