Do you think that taking ssri could help autoimmune symptoms of lupus

Since 90 percent of seratonin is found in the digestive tract, do u think that replenishing potentially
low seratonin levels would help make someone healthier physically?

Serotonin reuptake inhibitors serve to prolong the presence of serotonin within the synaptic clefts between its respective receptors in the brain. The neurotransmitter is chiefly involved in the conscious constructs of mood and appetite, as well in the maintenance of the circadian rhythm and sleep cycle. Gastrically-bound serotonin perpetuates the physiological response to hunger. As such, an SSRI achieves it effects by a neurological means -- that is, by influencing the brain to precipitate a desired response to a certain stimulus. Hence, I doubt such a pharmacologic application would be a viable treatment for lupus or any other autoimmune affliction occurring beyond the blood-brain barrier. That being said, there remains to be a study to affirm this doubt, and therefore, the therapeutic benefits of an SSRI upon immunological conditions remain to be measured. Taking into consideration the neurologically mediated control of the immune system, it might be plausible that an SSRI would produce some sort of response, however, the nature of such a reaction is yet to be discovered. Clinically low serotonin levels may benefit from a prescription of an SSRI, however, a life-threatening condition, Serotonin Syndrome, may result when the level of serotonin increases past an acceptable amount necessary to sustain healthy function.