Hydrogen bonding between valine and water
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Hydrogen bonding between valine and water

[From: ] [author: ] [Date: 12-09-13] [Hit: ]
water is not going to hydrogen bond with valines side chain.A hydrogen can only participate in a hydrogen bond if it is attached to an electronegative atom (e.g. OH, NH2).Carbon is not electronegative,......
I've been looking into the possibility of water hydrogen bonding with valine's side chain and I'm not sure if it's possible. In one respect the side chain is a nonpolar hydrocarbon molecule so how can it hydrogen bond to a water molecule? On the other hand may it be possible for water's oxygen to hydrogen bond to any one of the side chains hyrdrogens? What do you guys think?

The side chain of valine is -CH(CH3)2 a hydrocarbon

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No, water is not going to hydrogen bond with valine's side chain. A hydrogen can only participate in a hydrogen bond if it is attached to an electronegative atom (e.g. OH, NH2). Carbon is not electronegative, so the hydrogens of the side chain will not hydrogen bond.

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Of course not. Refer to the conditions or hydrogen bonding. Must have an O-H. Bond, F-H or N-H bond on one molecule , which is fulfilled by H2O but not the other criteria, i .e either an F, O or N atom on the other molecule, (with a lone pair). In this case, there is none on the side chain.
Hydrogen bonding cannot take place.
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