What percent of the total serum solute is sodium, is glucose, and is urea
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What percent of the total serum solute is sodium, is glucose, and is urea

[From: ] [author: ] [Date: 11-11-02] [Hit: ]
and even when we are concerned about amounts the usual way of calculating it has to do with serum osmolarity.However, in general terms, percentage-wise and assuming normal values, practically all of the solute is sodium.Under normal circumstances,......
If you don't have exact amounts that's fine, I just want close approximations.

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The answer is going to depend on whether or not the amounts of sodium, glucose and urea are normal or not, although sodium is always going to be most of it. Usually if they're normal we're not really concerned about percentages, and even when we are concerned about amounts the usual way of calculating it has to do with serum osmolarity.

However, in general terms, percentage-wise and assuming normal values, practically all of the solute is sodium. Under normal circumstances, there is relatively little free glucose or free urea floating around in the blood, whereas sodium is a normal and needed constituent of plasma. On top of that, when you look at them as solutes, sodium dissociates into Na+ and Cl-, so it makes up 'double' the amount.

I'm assuming this question has something to do with the fact that these are the three constituents of the blood that we sometimes adjust for when calculating serum osmolarity. If that's where it's coming from, think about the equation we use to adjust the Osm. You double the sodium and add glucose/18 and BUN/2.8. If I assume normal values and say sodium is 140, glucose is 100 and BUN is 10, then the serum osmolarity is 280 + 5.5 +3.6 = 289.1. The 280 is 97% of that.

Close enough of an approximation? ;-)

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