Which of the following structures will give a base peak of 43 in mass spectrometry
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Which of the following structures will give a base peak of 43 in mass spectrometry

[From: ] [author: ] [Date: 13-02-03] [Hit: ]
...\.........
http://i47.tinypic.com/sv3za0.gif

That is the answer but I am confused because I thought that compound would just lose a methyl group and the m/z would be 71.. what is the correct rule for fragmentation?

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The key is "base peak" meaning that it would be the peak with 100% abundance.

The compound shown (2,3-dimethylbutane):

H3C........CH3
.......\......./
.......CH-CH
......./.......\
H3C........CH3

(dots used as placeholders only)

is in essence two isopropyl groups (C3H7, m/z = 43), so fragmentation will result in a very high abundance of the ion having m/z of 43. The isopropyl radical cation is very stable and is favored over formation of other fragments, and thus it would be the base peak.

The mass spectrum does have a peak at m/z 71, but it isn't the base peak.

http://webbook.nist.gov/cgi/cbook.cgi?ID…
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