In Ireland, 3 out of 10,000 babies are infected with cystic fibrosis. Based on this info, what is the allele frequency for the recessive allele that causes cystic fibrosis?
A. Square root of 3/10,000
B. 2 x 3/10,000 x (1 - 3/10,000)
C. (3/10,000)^2
D. 10,000 choose 3 (binomial coefficient)
E. None of the above
Can you please help me with this question please and how to solve it?? Thank you !!!
A. Square root of 3/10,000
B. 2 x 3/10,000 x (1 - 3/10,000)
C. (3/10,000)^2
D. 10,000 choose 3 (binomial coefficient)
E. None of the above
Can you please help me with this question please and how to solve it?? Thank you !!!
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Here's the correct answer:
E. None of the above
Reasoning: You can't set up a Hardy-Weinberg equation with this population because the homozygous recessives don't generally have children of their own -- strong selection against the homozygotes here.
But your teacher probably does not want that answer. Your teacher probably wants the H-W equation answer.
p^2 + 2pq + q^2 = 1
where q^2 represents the homozygous recessives. So that would give you this answer:
A. Square root of 3/10,000
Up to you. Do you give the answer which is correct which will be marked wrong, or the answer which is wrong which will be marked as correct?
E. None of the above
Reasoning: You can't set up a Hardy-Weinberg equation with this population because the homozygous recessives don't generally have children of their own -- strong selection against the homozygotes here.
But your teacher probably does not want that answer. Your teacher probably wants the H-W equation answer.
p^2 + 2pq + q^2 = 1
where q^2 represents the homozygous recessives. So that would give you this answer:
A. Square root of 3/10,000
Up to you. Do you give the answer which is correct which will be marked wrong, or the answer which is wrong which will be marked as correct?