Can anyone help me with this Biology question please
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Can anyone help me with this Biology question please

[From: ] [author: ] [Date: 11-09-24] [Hit: ]
Square root of 3/10,B. 2 x 3/10,000 x (1 - 3/10,C. (3/10,......
In Ireland, 3 out of 10,000 babies are infected with cystic fibrosis. Based on this info, what is the allele frequency for the recessive allele that causes cystic fibrosis?

A. Square root of 3/10,000
B. 2 x 3/10,000 x (1 - 3/10,000)
C. (3/10,000)^2
D. 10,000 choose 3 (binomial coefficient)
E. None of the above


Can you please help me with this question please and how to solve it?? Thank you !!!

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Here's the correct answer:
E. None of the above
Reasoning: You can't set up a Hardy-Weinberg equation with this population because the homozygous recessives don't generally have children of their own -- strong selection against the homozygotes here.

But your teacher probably does not want that answer. Your teacher probably wants the H-W equation answer.
p^2 + 2pq + q^2 = 1
where q^2 represents the homozygous recessives. So that would give you this answer:
A. Square root of 3/10,000

Up to you. Do you give the answer which is correct which will be marked wrong, or the answer which is wrong which will be marked as correct?
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