Several structurally and functionally diverse proteins are encoded with the third region of the MHC. These molecules include several complement components include C2, C4a, C4b and factor B, two steroid hydroxylase enzymes include 21-hydoroxylase A, 21-hydroxylase B, the inflammatory cytokines include tumor necrosis factor a and b (TNF a and b) and two heat shock proteins (HSP 70). Unlike classI and class II MHC molecules, the class III molecules are not present on the surface of membranes. They are not related structurally to class I and class II molecules and have no role in antigen presentations.
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Very informative
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