LAB problems I need help with:
1) In a population of 100 individuals, if 42 have the genotype AA, 18 are AB and 40 are BB, then what are the genotype frequencies?
2) Based on the following experimental observations, what are the observed allele frequencies in the population? AA=10 individuals AB=30 individuals BB=10 individuals
3) Given the following allele frequencies, what are the expected genotype frequencies given Hardy-Weinberg equilibrium? A=0.60 B=0.40
1) In a population of 100 individuals, if 42 have the genotype AA, 18 are AB and 40 are BB, then what are the genotype frequencies?
2) Based on the following experimental observations, what are the observed allele frequencies in the population? AA=10 individuals AB=30 individuals BB=10 individuals
3) Given the following allele frequencies, what are the expected genotype frequencies given Hardy-Weinberg equilibrium? A=0.60 B=0.40
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2. You just need to add up all of your alleles. There are 50 As and 50 Bs for a total of 100 alleles. Simply divide the number of As (50) by the total number of alleles to get the frequency for A. Same goes for B.
3. You need to convert the allele frequencies (p = 0.60, q = 0.40):
p^2 = freq (AA), so square 0.60
2pq = freq (AB), so multiple 2(0.60)(0.40)
q^2 = freq (BB), so square 0.40
Then you multiply each of those results by the total individuals (n):
(p^2)n = expected AA individuals
(2pq)n = expected AB individuals
(q^2)n = expected BB individuals
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Your first question is basically questions two and three wrapped in one. You simply need to figure out the allele frequencies, as you do in question two (use the same procedure), and then convert those frequencies using the formulas from question three to find the genotype frequencies.
3. You need to convert the allele frequencies (p = 0.60, q = 0.40):
p^2 = freq (AA), so square 0.60
2pq = freq (AB), so multiple 2(0.60)(0.40)
q^2 = freq (BB), so square 0.40
Then you multiply each of those results by the total individuals (n):
(p^2)n = expected AA individuals
(2pq)n = expected AB individuals
(q^2)n = expected BB individuals
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Your first question is basically questions two and three wrapped in one. You simply need to figure out the allele frequencies, as you do in question two (use the same procedure), and then convert those frequencies using the formulas from question three to find the genotype frequencies.