Blood Glucose Regulation Biology Help please
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Blood Glucose Regulation Biology Help please

[From: ] [author: ] [Date: 11-10-22] [Hit: ]
The glucose then goes thru passive glucose channels into the bloodstream, away from the gut. Then the blood travels into the pancreas. Now the pancreatic cells take up the glucose, causing secretion of insulin into the bloodstream. Then the insulin reaches liver cells that have insulin receptors.......
I have a few questions about the process of Blood GLucose Regulation, can you please help? :)

In my bio notes, it says first the epithelial cells in the gut absorb glucose via glucose transporters. Are these transporters proteins?

The glucose then goes thru passive glucose channels into the bloodstream, away from the gut. Then the blood travels into the pancreas. Now the pancreatic cells take up the glucose, causing secretion of insulin into the bloodstream. Then the insulin reaches liver cells that have insulin receptors. So the blood reaches the pancreas first, and THEN it goes to the liver, in that order??

The insulin ligands bind to the insulin receptors of the liver cells, which causes the liver cell to secrete GLUT4- glucose transporters-into the liver cells' membranes. Are these the same glucose transporters which absorbed glucose into the gut?

Finally, after the release of GLUT4, the liver cells can take up glucose with the new GLUT4 in their plasma membranes.

I'm wondering why pancreas cells don't need GLUT4 to absorb glucose, but liver cells do...it seems like such a roundabout process I guess, lol. Any help would be appreciated!!! THANK YOU SO MUCH :)

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Yes, generally all transporters are transport proteins. The blood that is rich with glucose travels to the pancreas, then the pancreas creates insulin to balance the insulin/sugar ratio.

1) Blood takes glucose to the pancreas via the gut.
2) The pancreas then creates insulin to balance the ratio of insulin/sugar.
3) The insulin created by the pancreas is sent to the liver via the bloodstream.

It is not that the blood is reaching the pancreas and then the liver, what is important is what the blood is delivering. The blood delivers glucose to the pancreas so that insulin can be created, then the insulin is delivered to the insulin receptors in the liver. Blood is a connective tissue that acts like a moving sidewalk, its only function is to carry things to different parts of the body.
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