Blood Glucose Regulation Biology Help please

[From: ] [author: ] [Date: 11-10-22] [Hit: ]

GLUT4 is only used to transport glucose to areas of the body that need glucose.For example, when you exercise your muscles will send a signal saying Help I need glucose for energy! and the liver will send glucose saturated GLUT4 to the rescue.Think of it as GLUT2 absorbing the glucose in the liver, then the glucose is taken up by the GLUT4 for later use.......

GLUT-2 is used to transport glucose into the gut, pancreas and liver. (In that order)

GLUT-4 is used to carry glucose from the liver to the rest of the body. So the liver needs this in order to store and distribute to adipose and muscle tissue.

GLUT4 is only used to transport glucose to areas of the body that need glucose. For example, when you exercise your muscles will send a signal saying "Help I need glucose for energy!" and the liver will send glucose saturated GLUT4 to the rescue.

Think of it as GLUT2 absorbing the glucose in the liver, then the glucose is taken up by the GLUT4 for later use.

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o Glucose transporters are a wide group of membrane proteins

o yes - pancreas than liver ( the pancreas, raises blood glucose levels ....High blood glucose ... glucagon then encourages the liver to synthesize additional glucose

o no - the glucose transporters are not the same - there are two types (Glucose transporters can be divided into two groups. The facilitative glucose transporters (GLUTs) transport glucose into or out of the cell dependent on the glucose gradient. Under normal conditions, GLUTs transport glucose into the cell down its concentration gradient which is maintained by the rapid metabolism of glucose to glucose-6-phosphate as soon as it enters the cell. The sodium/glucose co-transporters (SGLT) require the co-transport of Na+ and can utilise the transmembrane Na+ gradient to drive concentrative glucose uptake

It should be noted here that there are some tissues that do not require insulin for efficient uptake of glucose: important examples are brain and the liver. This is because these cells don't use GLUT4 for importing glucose, but rather, another transporter that is not insulin-dependent.

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