The pituitary gland is the master gland

A. is completely accurate and appropriate.
B. Is completely inaccurate
C. is true; yet, is still controlled by the brain
D. Is a matter of debate since many other researchers refer to the adrenal gland as the master gland

The answer C more accurate. Pituitary is dubbed as the master gland as it controls the activities of the other glands such as thyroids, adrenals, etc. But the two lobes of Pituitary glands are under the control of the Hypothalamus. This hypothalamus is the part of the brain. One of the most important functions of the hypothalamus is to link the nervous system to the endocrine system via the pituitary gland (hypophysis). Hence, the answer C is justified.

C- it's located in the brain and secretes multiple necessary hormones for life functions but the hypothalamus is the master controller telling the pituitary gland what to release

I believe the answer is C. It is connected to the hypothalamus via the median eminence

C. is true; yet, is still controlled by the brain