Joan is a 35 year old woman whose mother died of Huntington’s disease. Neither Joan’s father nor her older brother show any signs of Huntington’s. What is the probability that Joan inherited the disease?
A. 25%
B. 50%
C. 75%
D. 100%
E. Her probability of inheriting the disease cannot be calculated without a genetic test.
Suppose a wooly mammoth is walking on top of a glacier, slips into a crack, and gets trapped. The animal freezes in the ice until the glacier starts to melt thousands of years later when a paleontologist recovers a small sample of the preserved animal. In order to compare the wooly mammoth’s DNA with DNA from living elephants, which of the following procedures should she use to increase the amount of DNA available to test?
A. Gel electrophoresis
B. Restriction fragment length polymorphism analysis
C. Polymerase chain reaction
D. Recombinant DNA technology
E. Gene therapy
Achondroplastic dwarfism is a dominant genetic trait that causes the head and torso of the body to develop normally, but the arms and legs to develop shorter than normal. The homozygous dominant condition is lethal, and the heterozygotes will be dwarfed. Mark has a family history of achondroplasia; however, he is not a dwarf. His wife, Susan, does express the trait. Mark and Susan are planning to have children and want to know the probability of having a child who is a dwarf.
The genotypes of the parents are most probably:
A. Mark AA; Susan Aa
B. Mark Aa; Susan aa
C. Mark aa; Susan aa
D. Mark aa; Susan Aa
E. Mark Aa; Susan Aa